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Coadministration of pexidartinib (a CYP3A4 inducer) with sensitive CYP3A substrates may well bring about severe therapeutic failures. If concomitant use is unavoidable, enhance the CYP3A substrate dosage in accordance with permitted product or service labeling.If coadministration of CYP3A4 inhibitors with fentanyl is necessary, keep track of patien